Some thoughtful, enthusiastic, investigative, exciting, inspiring statements of American stereochemist Karl Barry Sharpless

Karl Barry Sharpless (born April 28, 1941 in Philadelphia, Pennsylvania, USA) is an American stereochemist. He is a two-time Nobel Laureate in Chemistry, known for his work on stereoselective reactions and click chemistry. Sharpless was awarded half of the 2001 Nobel Prize in Chemistry for his work on chirally catalyzed oxidation reactions. A third of the 2022 awards go to Caroline R. Bertozzi and Morton P. Meldal, was awarded for the development of click chemistry. Sharpless is the fifth person (apart from two organizations) to be awarded the Nobel Prize twice, joining Marie Curie, John Bardeen, Linus Pauling, and Frederick Sanger, and the third person after Bardeen and Sanger to be awarded the Nobel Prize in the same discipline. Has been honored with two awards.

Karl Barry Sharpless Sharpless married Jan Dueser in 1965 and has three children. He lost the vision in one eye in 1970 during a laboratory accident where an NMR tube exploded, shortly after coming to MIT as an assistant professor. After this accident, Sharpless insisted, there is no good excuse for not wearing safety glasses at all times in the laboratory. In 2019 Sharpless was awarded the Priestley Medal, the American Chemical Society's highest honor, for his invention of catalysts, asymmetric oxidation methods, the concept of click chemistry, and the development of a copper-catalyzed version of the azide-acetylene cycloaddition reaction. The 2023 Gold Medal of the American Institute of Chemists was awarded to Carl Barry Sharpless.

Karl Barry Sharpless is Distinguished University Professor at Kyushu University. He holds honorary degrees from KTH Royal Institute of Technology (1995), Technical University of Munich (1995), Catholic University of Louvain (1996) and Wesleyan University (1999). Some of his thoughtful, enthusiastic, investigative, exciting, inspiring statements

The discipline is, nevertheless, strict that everything that can be seen must be seen, even if it is remembered only as a blurry background in which interesting fragments stand out, like Venus in the evening sky. The goal is always to discover something new, hopefully unimaginable and, even better, heretofore unimaginable.

What the ocean was to the child, what the periodic table was to the chemist.

We have a word game in English called Twenty Questions. To play Twenty Questions, one player imagines an object, and the other players must guess what it is by asking questions that can be answered with yes or no. I imagine there is a similar game in every language, and, for those of us who speak the language of science, this game is called the scientific method.

When I started doing chemistry, I did it the same way I did fishing – for the excitement, the discovery, the thrill, to catch the most elusive fish imaginable in an unknown sea.

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